Alum Precipitated Toxoid for the Prevention of Diphtheria
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چکیده
منابع مشابه
Studies on Tetanus Toxoid: III. Antitoxic Response in Guinea Pigs Immunized with Tetanus Alum-precipitated Toxoid Followed by Tetanus Spores.
When an individual has been given one or more injections of tetanus toxoid and, at a later date, is injured and possibly infected with Clostridium tetani, what further precautions should be taken: (1) Administer antitoxin? (2) Give another injection of tetanus toxoid to accelerate the production of antitoxin? (3) Give no further treatment, depending on his present immunity to take care of the i...
متن کاملImmunogenicity of IRIV- versus alum-adjuvanted diphtheria and tetanus toxoid vaccines in influenza primed mice.
The immunogenicity and protectivity of two different toxoid vaccines were compared in mice. In one formulation, toxoids (diphtheria or tetanus) were adsorbed to alumoxid, whereas in the other formulation the toxoids were crosslinked to immunopotentiating reconstituted influenza virosomes (IRIVs). A preimmunization with influenza antigens is necessary for a good anti-toxoid antibody response whe...
متن کاملThe Purification and Concentration of Diphtheria Toxoid
By precipitation with acetone at 4 degrees C. a refined diphtheria toxoid was obtained as a dry powder, readily soluble in aqueous solutions. The powder itself appears to be stable. When dissolved in half the original volume of physiological salt solution, the toxoid remained stable, in the cold room, for a period of 7 months. Only toxoids should be used which have been completely detoxified by...
متن کاملPrevention of pertussis among adolescents: recommendations for use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine.
The purpose of this statement is to provide the rationale and recommendations for adolescent use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccines. Despite universal immunization of children with multiple doses of pediatric diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine, pertussis remains endemic with a steady increase in the number of ...
متن کاملPreparation and Evaluation of Diphtheria Toxoid-Containing Microspheres
Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT. In the first step, following the purification of semi-crude DT by the ion-exchan...
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ژورنال
عنوان ژورنال: American Journal of Public Health and the Nations Health
سال: 1938
ISSN: 0002-9572
DOI: 10.2105/ajph.28.10.1170